T-01
Reconstitution calculator
Concentration, draw volume, U-100 syringe units, and doses per vial from vial size, water volume, and dose.
This calculator converts a sermorelin dose you have already been given by a licensed prescriber into the numbers you need at the syringe: concentration after reconstitution, injection volume, insulin-syringe units, and doses per vial. Compounded sermorelin ships in pharmacy-specific vial sizes; presets cover common listings and every field accepts any value.
Results
- Concentration
- 3 mg/mL3000 mcg/mL
- Volume per dose
- 0.1 mL
- U-100 syringe units per dose
- 10 unitsFits the 1 mL barrel (100 unit scale).
- Full doses per vial
- 20 doses
Arithmetic only: concentration = vial mg / water mL; units = mL x 100. It does not check any dose against any reference.
Worked example
Example: a 6 mg vial reconstituted with 2 mL of bacteriostatic water gives 6 / 2 = 3 mg/mL (math note). A prescribed 300 mcg dose is 0.3 mg divided by 3 mg/mL = 0.1 mL, which reads as 10 units on a U-100 syringe (math note). The vial holds 6000 / 300 = 20 doses (math note).
Step by step
- Check the vial's total peptide content on the pharmacy label.
- Draw the chosen volume of bacteriostatic water and add it to the vial slowly, aiming the stream at the glass wall, then swirl gently; do not shake.
- Compute concentration: vial contents divided by diluent volume.
- Convert the prescribed dose: dose divided by concentration gives injection volume; multiply millilitres by one hundred for units on a hundred-unit insulin syringe.
- Label the vial with the reconstitution date, refrigerate it, and follow the pharmacy's beyond-use date.
Doses used in the sermorelin literature (education, not recommendations)
| Setting | Regimen | Duration | Source | Source |
|---|---|---|---|---|
| Pediatric GHD (approved label era) | 30 mcg/kg SC nightly at bedtime | 12 months (trial) | Thorner 1996 | source |
| Healthy old men | 0.5 or 1.0 mg SC twice daily | 14 days per dose | Corpas 1992 | source |
| Healthy elderly men | 2 mg SC nightly | 6 weeks | Vittone 1997 | source |
| Ages 55-71, both sexes | 10 mcg/kg SC nightly (GHRH 1-29 analog) | 16 weeks | Khorram 1997 | source |
| Diagnostic test | 1 mcg/kg IV once | single dose | Prakash 1999 | source |
Frequently asked questions
How do mg, mcg, and syringe units relate?
One milligram is 1000 mcg, and a U-100 syringe marks volume: 100 units per mL, so units = mL x 100 math note. The peptide in each unit depends on reconstitution: at 3 mg/mL, 10 units (0.1 mL) carries 300 mcg math note.
One milligram is 1000 mcg, and a U-100 insulin syringe divides each millilitre into 100 units, so units are volume: units = mL x 100 math note. How much sermorelin each unit carries depends entirely on concentration: at 3 mg/mL, from a 6 mg vial with 2 mL of water, 10 units = 0.1 mL = 300 mcg math note.
Change the water volume and the same unit count delivers a different dose, which is why this calculator asks for vial size, diluent volume, and prescribed dose together.
How much water should go in the vial?
Whatever the pharmacy directs; the math simply follows math note. More water lowers concentration and enlarges each injection volume, easier to measure; less water concentrates it. Re-run the calculator whenever the volume changes.
Follow the dispensing pharmacy's instructions first; mathematically, any volume works and the calculator just re-derives concentration math note. More water means lower concentration and larger, easier-to-measure injection volumes; less water means smaller ones.
Very small volumes magnify syringe-marking error, a practical reason many pharmacy instructions choose volumes that put typical doses in a comfortably readable unit range math note. When the label specifies a volume, use it, and re-run the calculator if it ever changes.
How should the vial be stored after mixing?
Refrigerated, protected from light, used within the pharmacy's beyond-use date. The approved-era record documents refrigerated storage of the lyophilized product with a 24-month shelf life FDA 1991; solutions are less stable, so the pharmacy's dating controls.
Refrigerate the reconstituted vial, protect it from light, and observe the beyond-use date on the pharmacy label. For calibration: FDA's approval record for Geref documents lyophilized powder with a 24-month shelf life stored refrigerated FDA 1991. Solutions are less stable than powder, which is why beyond-use dates after mixing are short.
When storage instructions on the label and anything on this page disagree, the label wins; ask the dispensing pharmacist rather than a forum.
Which syringe size should I select?
The smallest that holds the computed volume, because finer graduations read more precisely math note. Short needles and systematic site rotation are the standing technique recommendations for subcutaneous injections Frid 2016.
Pick the smallest syringe that holds your computed volume, because finer graduations read more precisely; the calculator reports the volume so the choice is mechanical math note.
Technique guidance for subcutaneous therapy recommends short needles and systematic rotation of injection sites so lipohypertrophy does not develop Frid 2016. Our timing and rotation planner turns that recommendation into a printable schedule.
What if I mixed a different amount of water than planned?
Recompute before injecting anything: concentration follows the real volume, not the plan math note. A vial mixed with half the intended water carries double the peptide per unit, so an unchanged unit count would double the dose math note.
Recompute before injecting. Concentration follows what actually went into the vial: mix a 6 mg vial with 1 mL instead of 2 mL and it holds 6 mg/mL rather than 3, so the same 10 units now carries 600 mcg instead of 300 math note.
Enter the real vial size and the real water volume, read the corrected unit count for your prescribed dose, and if you are not sure what went in, the safe answer is the pharmacist, not an estimate.
Tools: educational calculators and references only.